Myo-inositol and D-chiro-inositol: what they are and how they're used
Irregular cycles, sugar cravings you can't control, tiredness after eating… For many women with polycystic ovary syndrome (PCOS), these signs have something in common: the way the body responds to insulin.
That's where myo-inositol and D-chiro-inositolcome in, two of the most-studied supplements in this field. Here's what they are, what the evidence says and how to take them.
What are inositols?
Inositol is a substance the body uses as a messenger inside cells, especially in the response to insulin. Myo-inositol and D-chiro-inositol are its two most important forms and they play complementary roles.
Why are they combined in a 40:1 ratio?
In the body, both are found in a ratio of roughly 40 parts myo-inositol to 1 part D-chiro-inositol. Several studies and reviews, such as the update published in Gynecological Endocrinology (2024), suggest that keeping that ratio gives better results than using high doses of D-chiro-inositol alone.
The ratio matters: 40:1 mimics the body's natural balance.
What is it used for?
- PCOS: reviews report improvements in metabolic markers, such as insulin sensitivity, and more regular cycles in some patients.
- Support for glucose control, as part of a healthy lifestyle.
The evidence is promising but still mixed. That's why it should be seen as a complement to medical treatment, never a replacement.
How to take it
Our Glycemic Control sachets combine myo-inositol and D-chiro-inositol with moringa, magnesium and vitamin D3, in 5 g sachets that dissolve easily in water.
- Dissolve one sachet in a glass of water.
- Take it daily, ideally at the same time.
- Pair it with a balanced diet and physical activity.
- Review with your doctor after at least 3 months.
Taking it with breakfast helps you remember it and is comfortable for most people.
Precautions
- It's usually well tolerated; at high doses it can cause mild stomach upset.
- If you take diabetes medication, check with your doctor: your glucose may need monitoring.
- If you're pregnant or trying to conceive, use it only on medical advice.
Frequently asked questions
Does it cause weight gain or weight loss?
It's not a weight-loss product. It can support metabolism as part of a comprehensive plan.
Can men take it?
Yes, as metabolic support and always after checking with their doctor.
Discover our Glycemic Control
Myo-inositol + D-chiro-inositol with moringa, magnesium and vitamin D3 in handy sachets.
Products mentioned
This article is for information only and does not replace an assessment by a health professional. Before starting any treatment or supplement, talk to your doctor, especially if you are pregnant, breastfeeding, taking medication or have a chronic condition.
Keep reading
Health and wellness · 3 min read
Hydrolyzed marine collagen: how to take it and what results to expect
Better-hydrated, more elastic skin: what science says about marine collagen, how to take it properly and how long results take.
Read article
Health and wellness · 3 min read
Minoxidil shampoo: does it work for hair loss?
What a minoxidil shampoo can and can't do, how to use it to get the most out of it and when to see a…
Read article
Health and wellness · 3 min read
Minoxidil for beard: how to use it, how long results take and precautions
Patchy beard? What the evidence says about minoxidil, how to apply it properly, when results show and what precautions…
Read article
